the future
of tissue

The Dental, Oral, and Craniofacial Tissue Regeneration Consortium (DOCTRC) was established in March 2017 through cooperative agreements from NIDCR, with the objective of developing resources and strategies to regenerate damaged or injured dental, oral, and craniofacial tissues. The DOCTRC initiative was designed to shepherd new therapies through pre-clinical studies and into human clinical trials, commercialization, and broad clinical adoption.




April 8, 2024

2024 MPWRM Resource Center
Stakeholder’s Summit

Ann Arbor, Michigan

Click here to Register by Feb 29th

See Schedule Here


Through the DOCTRC program, which originally provided support over three years, two national resource centers were developed:

Collective Impact

  • 20
    currently active Interdisciplinary Translational Projects
  • 65%
    currently active Interdisciplinary Translational Projects with FDA Interactions
  • 95%
    currently active Interdisciplinary Translational Projects with Issued Patents or Pending Applications
  • 228
    Project Proposals Reviewed
  • 44
    Interdisciplinary Translational Projects Awarded

NIDCR is confident that DOCTRC will set an example for the field of regenerative dentistry and regenerative medicine on how to take promising research findings over the Valley of Death through translational pipeline toward clinical trials and adoption by clinical practice.

Nadya Lumelsky, PhD
Project Scientist on DOCTRC Program
Director, Tissue Engineering and Regenerative Medicine Program
Chief, Integrative Biology and Infectious Diseases Branch
Meet Our People

Core Expertise + Services


With the overarching goal of developing clinical trial-ready tissue engineering/regenerative medicine products and protocols, the DOCTRC initiative is providing funding and resources through the Interdisciplinary Translational Project (ITP) program.

View Our ITP Portfolio


Formally launched in March 2017 with support from our sponsor, National Institute of Dental and Craniofacial Research (NIDCR), DOCTRC strives to shepherd promising regenerative medicine technologies towards initiation of clinical trials and beyond. As a single Consortium, C-DOCTOR and MPWRM Resource Center have collectively supported 36 Interdisciplinary Translational Projects to date.