Defining
the future
of tissue
regeneration.

The Dental, Oral, and Craniofacial Tissue Regeneration Consortium (DOCTRC) was established in March 2017 through cooperative agreements from NIDCR, with the objective of developing resources and strategies to regenerate damaged or injured dental, oral, and craniofacial tissues. The DOCTRC initiative was designed to shepherd new therapies through pre-clinical studies and into human clinical trials, commercialization, and broad clinical adoption.

 

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Oct 21-23, 2024

DOCTRC RETREAT

Bethesda, MD

 

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Through the DOCTRC program, which originally provided support over three years, two national resource centers were developed:

Collective Impact

  • 16
    currently active Interdisciplinary Translational Projects
  • 63%
    currently active Interdisciplinary Translational Projects with FDA Interactions
  • 94%
    currently active Interdisciplinary Translational Projects with Issued Patents or Pending Applications
  • 228
    Project Proposals Reviewed
  • 44
    Interdisciplinary Translational Projects Awarded

NIDCR’s vision was that the DOCTRC could act as a catalyst to accelerate translation of innovative products in the dental, oral, and craniofacial regenerative medicine space. The strategy was to build a consortium infrastructure that would provide the tools and expertise needed to enable academic, clinical, and industry innovators to overcome the key translational, regulatory, and commercial barriers, often referred to as the Valley of Death. While this program is still ongoing, we are extremely proud of the accomplishments that the DOCTRC has already achieved, and we are hopeful that this mechanism will serve as a proven template for future efforts seeking to bring dental as well as medical innovations to the full benefit of patients.

Scott S. Verbridge, PhD
Director, Tissue Engineering and Regenerative Medicine Program
NIDCR, NIH
Meet Our People

Core Expertise + Services

Portfolio

With the overarching goal of developing clinical trial-ready tissue engineering/regenerative medicine products and protocols, the DOCTRC initiative is providing funding and resources through the Interdisciplinary Translational Project (ITP) program.

View Our ITP Portfolio

Partners

Formally launched in March 2017 with support from our sponsor, National Institute of Dental and Craniofacial Research (NIDCR), DOCTRC strives to shepherd promising regenerative medicine technologies towards initiation of clinical trials and beyond. As a single Consortium, C-DOCTOR and MPWRM Resource Center have collectively supported 36 Interdisciplinary Translational Projects to date.