Portfolio

Interdisciplinary Translational Projects Supported
Principal Investigator(s) ITP Project Title Technology Type
Bone
Tara Aghaloo, DDS, MD, PhD (University of California Los Angeles) Stem cell-based therapies for bone regeneration around ailing dental implants Biologic‑Device
Yang Chai, DDS, PhD (University of Southern California) Calvarial bone regeneration using mesenchymal stem cells Biologic‑Device
Joseph Fiorellini, DMD, DMedSc (Penn Dental Medicine), George Kay, DMD (RevBio) Optimization of a Novel Organic-Mineral Bone Adhesive for Dental Bone Grafting (Tetranite) Device
Andrew Brown, PhD (Emergence Dental)/​Stephen LeBeau, PhD (nanoMAG) AmpliMag: Form Stable, Resorbable Barrier Membrane Device
Ari Wes, MD (Ostiio) Ostiio: A Smart, Fully-Implantable CMF Distractor Device
Brad Amendt, PhD (University of Iowa & NaturemIRI, LLC) MicroRNA Mediated Alveolar Ridge Preservation and Augmentation Device
Ramille Shah, PhD (Dimension Inx) Customizable CMFlex(TM) Bone Grafts for Craniomaxillofacial Bone Defect Applications Device
William Giannobile, DDS, DMedSc (Harvard University) Abaloparatide to Treat Alveolar Bone Loss for Dental Implant Reconstruction Biologic‑Device
Periodontal Tissues
Steven Little, PhD/​Charles Sfeir, DDS, PhD (University of Pittsburgh) Immunomodulatory Strategies to Treat Periodontal Disease (CCL2/​22) Biologic
Song Li, PhD (University of California Los Angeles) Immunomodulatory periodontal microneedle patch for tissue regeneration - periodontal tissues, drug-device Drug-Device
Salivary Gland
Michael Passineau, PhD (Allegheny Health Network)/​Isabelle Lombaert, PhD (University of Michigan) Non-viral Aquaporin-1 Gene Therapy to Restore Salivary Flow in Patients Suffering from Radiation-induced Xerostomia, Michael Passineau, PhD (Allegheny Health Network)/​Isabelle Lombaert, PhD (University of Michigan) Biologic‑Device
Sarah Knox, PhD (University of California San Francisco) Hydronova: Regenerating the salivary gland using an injectable hydrogel Drug‑Device
Soft Tissue (Nerve, Muscle, Skin, Fat, Other)
Stephen Feinberg, DDS, PhD (University of Michigan) Tissue Engineering Functional Human Lips Biologic
J. Peter Rubin, MD (University of Pittsburgh) A Device to Preserve Adipose Tissue Grafts for Soft Tissue Reconstruction (LipoStore) Device
Kevin Healy, PhD (University of California Berkeley) Bioinspired hydrogels for craniofacial muscle regeneration Device
Derrick Wan, MD (Stanford University) Transdermal deferoxamine to enhance fat graft retention for reconstruction of irradiated soft tissue defects Drug‑Device
Geoffrey Gurtner, MD (Stanford University) Prevention of scar formation in the skin using topical focal adhesion kinase inhibitors Drug‑Device
Jamie Murbach, PhD (Amend Surgical, Inc.) Tough Adhesive for Oral Wound Care Device
Michael Longaker, MD, MBA (Stanford University) Local injection of verteporfin to promote wound repair via regeneration without scarring in primary cleft lip repair Drug
Teeth/​Dental Pulp
Luiz Bertassoni, DDS, PhD (Oregon Health and Science University)/​Pamela Yelick, PhD (Tufts University) REGEndogel: A Bioinspired Hydrogel System for Endodontic Therapy Device
Steven Bloembergen, PhD (GreenMark Biomedical) Targeted Remineralization Treatment Using Mineral Loaded Starch Nanoparticle Device
Juan Taboas, PhD/​Herb Ray, DMD (University of Pittsburgh) Commercialization of Vital-Dent Drug‑device
Temporomandibular Joint
Denis Evseenko, MD, PhD (University of Southern California) Novel drug candidate for therapy of arthritis of the temporomandibular joint Drug

Currently Supported ITP Portfolio

Institution

Tissue Addressed

Technology Type