Defining
the future
of tissue
regeneration.

The Dental, Oral, and Craniofacial Tissue Regeneration Consortium (DOCTRC) was established in March 2017 through cooperative agreements from NIDCR, with the objective of developing resources and strategies to regenerate damaged or injured dental, oral, and craniofacial tissues. The DOCTRC initiative was designed to shepherd new therapies through pre-clinical studies and into human clinical trials, commercialization, and broad clinical adoption.

The Ultimate Goal

To develop strategies and devices that could help repair or regenerate damaged DOC tissues, including:

  • Bone
  • Muscle + Nerve + Skin + Soft Tissue
  • Temporomandibular Joint
  • Periodontal Tissues
  • Salivary Gland
  • Teeth + Dental Pulp

Through the DOCTRC program, which originally provided support over three years, two national resource centers were developed:

Collective Impact

  • 170
    Project Proposals Reviewed
  • 36
    Interdisciplinary Translational Projects Awarded
  • 50
    % of Interdisciplinary Translational Projects with FDA Interactions
  • 95
    % of Interdisciplinary Translational Projects with Issued Patents or Pending Applications

NIDCR is confident that DOCTRC will set an example for the field of regenerative dentistry and regenerative medicine on how to take promising research findings over the Valley of Death through translational pipeline toward clinical trials and adoption by clinical practice.

Nadya Lumelsky, PhD
Project Scientist on DOCTRC Program
Director, Tissue Engineering and Regenerative Medicine Program
Chief, Integrative Biology and Infectious Diseases Branch
NIDCR, NIH
Meet Our People

Core Expertise + Services

Portfolio

With the overarching goal of developing clinical trial-ready tissue engineering/regenerative medicine products and protocols, the DOCTRC initiative is providing funding and resources through the Interdisciplinary Translational Project (ITP) program.

View Our ITP Portfolio

Partners

Formally launched in March 2017 with support from our sponsor, National Institute of Dental and Craniofacial Research (NIDCR), DOCTRC strives to shepherd promising regenerative medicine technologies towards initiation of clinical trials and beyond. As a single Consortium, C-DOCTOR and MPWRM Resource Center have collectively supported 36 Interdisciplinary Translational Projects to date.