Dental, Oral & Craniofacial
Tissue Regeneration Consortium
Tissue Regeneration Consortium
Portfolio
| Principal Investigator(s) | ITP Project Title | Technology Type | Regulatory Path |
|---|---|---|---|
| Bone | |||
| Tara Aghaloo, DDS, MD, PhD (University of California Los Angeles) | Stem cell-based therapies for bone regeneration around ailing dental implants | Biologic‑Device | IDE |
| Yang Chai, DDS, PhD (University of Southern California) | Calvarial bone regeneration using 3D printed scaffold and bone marrow aspirate | Biologic‑Device | IDE |
| Joseph Fiorellini, DMD, DMedSc (Penn Dental Medicine), George Kay, DMD (RevBio) | Optimization of a Novel Organic-Mineral Bone Adhesive for Dental Bone Grafting (Tetranite) | Device | IDE |
| Ari Wes, MD (Ostiio) | Ostiio: A Smart, Fully-Implantable CMF Distractor | Device | 510(k) |
| Salivary Gland | |||
| Isabelle Lombaert, PhD (University of Michigan)/Michael Passineau, PhD (Allegheny Health Network) | Non-viral Aquaporin-1 Gene Therapy to Restore Salivary Flow in Patients Suffering from Radiation-induced Xerostomia, Michael Passineau, PhD (Allegheny Health Network)/Isabelle Lombaert, PhD (University of Michigan) | Biologic‑Device | IND |
| Sarah Knox, PhD (University of California San Francisco) | Hydronovo: Regenerating the salivary gland using an injectable hydrogel | Drug‑Device | IND 505(b)(2) |
| Soft Tissue (Fat, Muscle, Nerve, Skin, Other) | |||
| Robby Lane, MBA (Amend Surgical, Inc.) | Suture-less Trigeminal Nerve Repair Device | Device | 510(k) |
| Kevin Healy, PhD (University of California Berkeley) | Bioinspired hydrogels for craniofacial muscle regeneration | Device | de novo PMA |
| Derrick Wan, MD (Stanford University) | Transdermal deferoxamine to enhance fat graft retention for reconstruction of irradiated soft tissue defects | Drug‑Device | IND 505(b)(2) opened |
| Geoffrey Gurtner, MD (Stanford University) | Prevention of scar formation in the skin using topical focal adhesion kinase inhibitors | Drug‑Device | IND 505(b)(2) |
| Jamie Shaikoski, PhD (Amend Surgical, Inc.) | Amend Tissue Tape™ for Oral Wound Care | Device | 510(k) |
| Michael Longaker, MD, MBA (Stanford University) | Local injection of verteporfin to promote wound repair via regeneration without scarring in primary cleft lip repair | Drug | IND 505(b)(2) |
| Jon-Paul Pepper, MD (Stanford University) | Drug loaded, bioprinted fibrin scaffolds for use during cranial nerve repair surgery | Drug-Device | IND |
| Teeth/Dental Pulp | |||
| Luiz Bertassoni, DDS, PhD (Oregon Health and Science University)/Pamela Yelick, PhD (Tufts University) | REGEndogel: A Bioinspired Hydrogel System for Endodontic Therapy | Device | IDE |
| Steven Bloembergen, PhD (GreenMark Biomedical) | Targeted Remineralization Treatment Using Mineral Loaded Starch Nanoparticle | Device | 510(k) |
| Juan Taboas, PhD/Herb Ray, DMD (University of Pittsburgh) | Commercialization of Vital-Dent | Device | 510(k) |
Currently Supported ITP Portfolio
Institution
Tissue Addressed
Regulatory Pathway
